Direct (nonstop) flights from Des Moines to Chicago
1 airline flys nonstop from Des Moines International (DSM) to Chicago Midway International (MDW). It's 306 miles (492 km), about 1h 20m in the air. Operated by Southwest Airlines.
Southwest Airlines
Route data last updated: May 26, 2026
Airlines with non-stop flights
WN
Southwest Airlines
Alternative Routes
Other ways to fly from Des Moines to Chicago with one stop · direct emits 57 kg CO₂ per passenger
Looking for the return flight?
MDW → DSM: Flights from Chicago to Des MoinesOther direct flights from Des Moines
Direct flights from Chicago (MDW)
Frequently Asked Questions
How long is the direct flight from Des Moines to Chicago?
A nonstop flight from Des Moines (DSM) to Chicago (MDW) takes approximately 1 hours and 20 minutes. The distance is 306 miles (492 km).
Which airlines fly nonstop from Des Moines to Chicago?
Just Southwest Airlines.
Is there a nonstop flight from Des Moines to Chicago?
Yes. 1 airline: Southwest Airlines.
How far is Des Moines from Chicago?
The flight distance from Des Moines to Chicago is 306 miles (492 km), measured as the great-circle (shortest air) distance. That's roughly the same distance as Mumbai to Goa.
What type of aircraft flies from Des Moines to Chicago?
At 1h 20m, this route typically uses narrow-body aircraft — Boeing 737 or Airbus A320. Varies by airline.
What is the carbon footprint of a flight from Des Moines to Chicago?
Roughly 57 kg CO2 per passenger one-way. That's about the same as driving 285 km.
Is the return flight from Chicago to Des Moines also nonstop?
Yes — nonstop flights run both ways. Flight time may differ slightly due to wind patterns.
When is the cheapest time to fly from Des Moines to Chicago?
Midweek flights (Tue/Wed) outside holiday peaks are usually cheapest. 3-6 weeks ahead is a good window for this route. Use "Check Prices" above to compare.
How early should I arrive at Des Moines International for this flight?
1.5-2 hours for domestic. Add more time during holidays or busy travel weekends.