Direct (nonstop) flights from Panama City to Chicago
1 airline flys nonstop from Panama City-NW Florida Bea. (ECP) to Chicago Midway International (MDW). It's 795 miles (1,280 km), about 2h 18m in the air. Operated by Southwest Airlines.
Southwest Airlines
Route data last updated: May 29, 2026
Airlines with non-stop flights
WN
Southwest Airlines
Alternative Routes
Other ways to fly from Panama City to Chicago with one stop · direct emits 147 kg CO₂ per passenger
Looking for the return flight?
MDW → ECP: Flights from Chicago to Panama CityOther direct flights from Panama City
Direct flights from Chicago (MDW)
Frequently Asked Questions
How long is the direct flight from Panama City to Chicago?
A nonstop flight from Panama City (ECP) to Chicago (MDW) takes approximately 2 hours and 18 minutes. The distance is 795 miles (1,280 km).
Which airlines fly nonstop from Panama City to Chicago?
Just Southwest Airlines.
Is there a nonstop flight from Panama City to Chicago?
Yes. 1 airline: Southwest Airlines.
How far is Panama City from Chicago?
The flight distance from Panama City to Chicago is 795 miles (1,280 km), measured as the great-circle (shortest air) distance. That's roughly the same distance as London to Madrid.
What type of aircraft flies from Panama City to Chicago?
At 2h 18m, this route typically uses narrow-body or mid-range jets — Boeing 737 MAX or Airbus A320neo. Varies by airline.
What is the carbon footprint of a flight from Panama City to Chicago?
Roughly 147 kg CO2 per passenger one-way. That's about the same as driving 735 km.
Is the return flight from Chicago to Panama City also nonstop?
Yes — nonstop flights run both ways. Flight time may differ slightly due to wind patterns.
When is the cheapest time to fly from Panama City to Chicago?
Midweek flights (Tue/Wed) outside holiday peaks are usually cheapest. 3-6 weeks ahead is a good window for this route. Use "Check Prices" above to compare.
How early should I arrive at Panama City-NW Florida Bea. for this flight?
1.5-2 hours for domestic. Add more time during holidays or busy travel weekends.