Direct (nonstop) flights from Saint Louis to Panama City
1 airline flys nonstop from Saint Louis Airport (STL) to Panama City-NW Florida Bea. (ECP). It's 634 miles (1,021 km), about 1h 45m in the air. Operated by Southwest Airlines.
Southwest Airlines
Route data last updated: May 28, 2026
Airlines with non-stop flights
WN
Southwest Airlines
Alternative Routes
Other ways to fly from Saint Louis to Panama City with one stop · direct emits 117 kg CO₂ per passenger
Looking for the return flight?
ECP → STL: Flights from Panama City to Saint LouisOther direct flights from Saint Louis
Direct flights from Panama City (ECP)
Frequently Asked Questions
How long is the direct flight from Saint Louis to Panama City?
A nonstop flight from Saint Louis (STL) to Panama City (ECP) takes approximately 1 hours and 45 minutes. The distance is 634 miles (1,021 km).
Which airlines fly nonstop from Saint Louis to Panama City?
Just Southwest Airlines.
Is there a nonstop flight from Saint Louis to Panama City?
Yes. 1 airline: Southwest Airlines.
How far is Saint Louis from Panama City?
The flight distance from Saint Louis to Panama City is 634 miles (1,021 km), measured as the great-circle (shortest air) distance. That's roughly the same distance as the length of Italy.
What type of aircraft flies from Saint Louis to Panama City?
At 1h 45m, this route typically uses narrow-body aircraft — Boeing 737 or Airbus A320. Varies by airline.
What is the carbon footprint of a flight from Saint Louis to Panama City?
Roughly 117 kg CO2 per passenger one-way. That's about the same as driving 585 km.
Is the return flight from Panama City to Saint Louis also nonstop?
Yes — nonstop flights run both ways. Flight time may differ slightly due to wind patterns.
When is the cheapest time to fly from Saint Louis to Panama City?
Midweek flights (Tue/Wed) outside holiday peaks are usually cheapest. 3-6 weeks ahead is a good window for this route. Use "Check Prices" above to compare.
How early should I arrive at Saint Louis Airport for this flight?
1.5-2 hours for domestic. Add more time during holidays or busy travel weekends.