Direct (nonstop) flights from Myrtle Beach to Saint Louis

1 airline flys nonstop from Myrtle Beach International Airport (MYR) to Saint Louis Airport (STL). It's 728 miles (1,172 km), about 2h 5m in the air. Operated by Southwest Airlines.

MYR
Myrtle Beach International Airport
🇺🇸 Myrtle Beach, USA
STL
Saint Louis Airport
🇺🇸 Saint Louis, USA
Flight Time
2h 5m
Distance
728 mi
1,172 km
CO₂/pax
135 kg
−40 kg vs. layover
Airlines
1
Southwest Airlines
Time Diff
-1h
Operated by Southwest Airlines Southwest Airlines

Route data last updated: May 28, 2026

Airlines with non-stop flights

Southwest Airlines WN Southwest Airlines
Route
MYR → STL
Flight Time
2h 5m
Distance
728 mi

Alternative Routes

Other ways to fly from Myrtle Beach to Saint Louis with one stop · direct emits 135 kg CO₂ per passenger

MYR IND (Indianapolis) STL
Leg 1: 1h 49m (583 mi) Leg 2: 1h (229 mi) Total: ~2h 49m 🍃 175 kg CO₂ (+30% vs. direct)
Leg 1
MYR → IND
1h 49m · 583 mi
View MYR to IND flights →
Leg 2
IND → STL
1h · 229 mi
View IND to STL flights →
MYR BNA (Nashville) STL
Leg 1: 1h 35m (470 mi) Leg 2: 1h 15m (272 mi) Total: ~2h 50m 🍃 162 kg CO₂ (+20% vs. direct)
Leg 1
MYR → BNA
1h 35m · 470 mi
View MYR to BNA flights →
Leg 2
BNA → STL
1h 15m · 272 mi
View BNA to STL flights →
MYR CMH (Columbus) STL
Leg 1: 1h 30m (487 mi) Leg 2: 1h 30m (410 mi) Total: ~3h 🍃 191 kg CO₂ (+41% vs. direct)
Leg 1
MYR → CMH
1h 30m · 487 mi
View MYR to CMH flights →
Leg 2
CMH → STL
1h 30m · 410 mi
View CMH to STL flights →
MYR ATL (Atlanta) STL
Leg 1: 1h 25m (318 mi) Leg 2: 1h 42m (483 mi) Total: ~3h 7m 🍃 173 kg CO₂ (+28% vs. direct)
Leg 1
MYR → ATL
1h 25m · 318 mi
View MYR to ATL flights →
Leg 2
ATL → STL
1h 42m · 483 mi
View ATL to STL flights →
MYR PIT (Pittsburgh) STL
Leg 1: 1h 30m (475 mi) Leg 2: 1h 45m (552 mi) Total: ~3h 15m 🍃 215 kg CO₂ (+59% vs. direct)
Leg 1
MYR → PIT
1h 30m · 475 mi
View MYR to PIT flights →
Leg 2
PIT → STL
1h 45m · 552 mi
View PIT to STL flights →

Frequently Asked Questions

How long is the direct flight from Myrtle Beach to Saint Louis?

A nonstop flight from Myrtle Beach (MYR) to Saint Louis (STL) takes approximately 2 hours and 5 minutes. The distance is 728 miles (1,172 km).

Which airlines fly nonstop from Myrtle Beach to Saint Louis?

Just Southwest Airlines.

Is there a nonstop flight from Myrtle Beach to Saint Louis?

Yes. 1 airline: Southwest Airlines.

How far is Myrtle Beach from Saint Louis?

The flight distance from Myrtle Beach to Saint Louis is 728 miles (1,172 km), measured as the great-circle (shortest air) distance. That's roughly the same distance as the length of Italy.

What type of aircraft flies from Myrtle Beach to Saint Louis?

At 2h 5m, this route typically uses narrow-body or mid-range jets — Boeing 737 MAX or Airbus A320neo. Varies by airline.

What is the carbon footprint of a flight from Myrtle Beach to Saint Louis?

Roughly 135 kg CO2 per passenger one-way. That's about the same as driving 675 km.

Is the return flight from Saint Louis to Myrtle Beach also nonstop?

Yes — nonstop flights run both ways. Flight time may differ slightly due to wind patterns.

When is the cheapest time to fly from Myrtle Beach to Saint Louis?

Midweek flights (Tue/Wed) outside holiday peaks are usually cheapest. 3-6 weeks ahead is a good window for this route. Use "Check Prices" above to compare.

How early should I arrive at Myrtle Beach International Airport for this flight?

1.5-2 hours for domestic. Add more time during holidays or busy travel weekends.