Direct (nonstop) flights from Saint Louis to Des Moines
1 airline flys nonstop from Saint Louis Airport (STL) to Des Moines International (DSM). It's 258 miles (416 km), about 1h 10m in the air. Operated by Southwest Airlines.
Southwest Airlines
Route data last updated: May 24, 2026
Airlines with non-stop flights
WN
Southwest Airlines
Alternative Routes
Other ways to fly from Saint Louis to Des Moines with one stop · direct emits 48 kg CO₂ per passenger
Looking for the return flight?
DSM → STL: Flights from Des Moines to Saint LouisOther direct flights from Saint Louis
Direct flights from Des Moines (DSM)
Frequently Asked Questions
How long is the direct flight from Saint Louis to Des Moines?
A nonstop flight from Saint Louis (STL) to Des Moines (DSM) takes approximately 1 hours and 10 minutes. The distance is 258 miles (416 km).
Which airlines fly nonstop from Saint Louis to Des Moines?
Just Southwest Airlines.
Is there a nonstop flight from Saint Louis to Des Moines?
Yes. 1 airline: Southwest Airlines.
How far is Saint Louis from Des Moines?
The flight distance from Saint Louis to Des Moines is 258 miles (416 km), measured as the great-circle (shortest air) distance. That's roughly the same distance as London to Paris.
What type of aircraft flies from Saint Louis to Des Moines?
At 1h 10m, this route typically uses narrow-body aircraft — Boeing 737 or Airbus A320. Varies by airline.
What is the carbon footprint of a flight from Saint Louis to Des Moines?
Roughly 48 kg CO2 per passenger one-way. That's about the same as driving 240 km.
Is the return flight from Des Moines to Saint Louis also nonstop?
Check the DSM to STL route page for return options.
When is the cheapest time to fly from Saint Louis to Des Moines?
Midweek flights (Tue/Wed) outside holiday peaks are usually cheapest. 3-6 weeks ahead is a good window for this route. Use "Check Prices" above to compare.
How early should I arrive at Saint Louis Airport for this flight?
1.5-2 hours for domestic. Add more time during holidays or busy travel weekends.