Direct (nonstop) flights from Denver to Knoxville
4 airlines fly nonstop from Denver International (DEN) to Mc Ghee Tyson (TYS). It's 1,162 miles (1,870 km), about 2h 49m in the air. Operated by Frontier Airlines, Allegiant Air, United Airlines and others.
Frontier Airlines
Allegiant Air
United Airlines
Southwest Airlines
Route data last updated: May 30, 2026
Airlines with non-stop flights
F9
Frontier Airlines
UA
United Airlines
WN
Southwest Airlines
Alternative Routes
Other ways to fly from Denver to Knoxville with one stop · direct emits 196 kg CO₂ per passenger
Looking for the return flight?
TYS → DEN: Flights from Knoxville to DenverOther direct flights from Denver
Direct flights from Knoxville (TYS)
Frequently Asked Questions
How long is the direct flight from Denver to Knoxville?
A nonstop flight from Denver (DEN) to Knoxville (TYS) takes approximately 2 hours and 49 minutes. The distance is 1,162 miles (1,870 km).
Which airlines fly nonstop from Denver to Knoxville?
4 airlines: Frontier Airlines, Allegiant Air, United Airlines, Southwest Airlines.
Is there a nonstop flight from Denver to Knoxville?
Yes. 4 airlines: Frontier Airlines, Allegiant Air, United Airlines, Southwest Airlines.
How far is Denver from Knoxville?
The flight distance from Denver to Knoxville is 1,162 miles (1,870 km), measured as the great-circle (shortest air) distance. That's roughly the same distance as New York to Miami.
What type of aircraft flies from Denver to Knoxville?
At 2h 49m, this route typically uses narrow-body or mid-range jets — Boeing 737 MAX or Airbus A320neo. Varies by airline.
What is the carbon footprint of a flight from Denver to Knoxville?
Roughly 196 kg CO2 per passenger one-way. That's about the same as driving 980 km.
Is the return flight from Knoxville to Denver also nonstop?
Yes — nonstop flights run both ways. Flight time may differ slightly due to wind patterns.
When is the cheapest time to fly from Denver to Knoxville?
Midweek flights (Tue/Wed) outside holiday peaks are usually cheapest. 3-6 weeks ahead is a good window for this route. Use "Check Prices" above to compare.
How early should I arrive at Denver International for this flight?
1.5-2 hours for domestic. Add more time during holidays or busy travel weekends.