Direct (nonstop) flights from Chicago to Knoxville
1 airline flys nonstop from Chicago Midway International (MDW) to Mc Ghee Tyson (TYS). It's 459 miles (739 km), about 1h 27m in the air. Operated by Allegiant Air.
Allegiant Air
Route data last updated: May 31, 2026
Airlines with non-stop flights
Alternative Routes
Other ways to fly from Chicago to Knoxville with one stop · direct emits 85 kg CO₂ per passenger
Looking for the return flight?
TYS → MDW: Flights from Knoxville to ChicagoOther direct flights from Chicago
Direct flights from Knoxville (TYS)
Frequently Asked Questions
How long is the direct flight from Chicago to Knoxville?
A nonstop flight from Chicago (MDW) to Knoxville (TYS) takes approximately 1 hours and 27 minutes. The distance is 459 miles (739 km).
Which airlines fly nonstop from Chicago to Knoxville?
Just Allegiant Air.
Is there a nonstop flight from Chicago to Knoxville?
Yes. 1 airline: Allegiant Air.
How far is Chicago from Knoxville?
The flight distance from Chicago to Knoxville is 459 miles (739 km), measured as the great-circle (shortest air) distance. That's roughly the same distance as Mumbai to Goa.
What type of aircraft flies from Chicago to Knoxville?
At 1h 27m, this route typically uses narrow-body aircraft — Boeing 737 or Airbus A320. Varies by airline.
What is the carbon footprint of a flight from Chicago to Knoxville?
Roughly 85 kg CO2 per passenger one-way. That's about the same as driving 425 km.
Is the return flight from Knoxville to Chicago also nonstop?
Yes — nonstop flights run both ways. Flight time may differ slightly due to wind patterns.
When is the cheapest time to fly from Chicago to Knoxville?
Midweek flights (Tue/Wed) outside holiday peaks are usually cheapest. 3-6 weeks ahead is a good window for this route. Use "Check Prices" above to compare.
How early should I arrive at Chicago Midway International for this flight?
1.5-2 hours for domestic. Add more time during holidays or busy travel weekends.