Direct (nonstop) flights from Chicago to Knoxville
2 airlines fly nonstop from Chicago O Hare International (ORD) to Mc Ghee Tyson (TYS). It's 475 miles (764 km), about 1h 45m in the air. Operated by American Airlines, United Airlines.
American Airlines
United Airlines
Route data last updated: May 28, 2026
Airlines with non-stop flights
AA
American Airlines
UA
United Airlines
Alternative Routes
Other ways to fly from Chicago to Knoxville with one stop · direct emits 88 kg CO₂ per passenger
Looking for the return flight?
TYS → ORD: Flights from Knoxville to ChicagoOther direct flights from Chicago
Direct flights from Knoxville (TYS)
Frequently Asked Questions
How long is the direct flight from Chicago to Knoxville?
A nonstop flight from Chicago (ORD) to Knoxville (TYS) takes approximately 1 hours and 45 minutes. The distance is 475 miles (764 km).
Which airlines fly nonstop from Chicago to Knoxville?
2 airlines: American Airlines, United Airlines.
Is there a nonstop flight from Chicago to Knoxville?
Yes. 2 airlines: American Airlines, United Airlines.
How far is Chicago from Knoxville?
The flight distance from Chicago to Knoxville is 475 miles (764 km), measured as the great-circle (shortest air) distance. That's roughly the same distance as Mumbai to Goa.
What type of aircraft flies from Chicago to Knoxville?
At 1h 45m, this route typically uses narrow-body aircraft — Boeing 737 or Airbus A320. Varies by airline.
What is the carbon footprint of a flight from Chicago to Knoxville?
Roughly 88 kg CO2 per passenger one-way. That's about the same as driving 440 km.
Is the return flight from Knoxville to Chicago also nonstop?
Yes — nonstop flights run both ways. Flight time may differ slightly due to wind patterns.
When is the cheapest time to fly from Chicago to Knoxville?
Midweek flights (Tue/Wed) outside holiday peaks are usually cheapest. 3-6 weeks ahead is a good window for this route. Use "Check Prices" above to compare.
How early should I arrive at Chicago O Hare International for this flight?
1.5-2 hours for domestic. Add more time during holidays or busy travel weekends.