Direct (nonstop) flights from Knoxville to Chicago
1 airline flys nonstop from Mc Ghee Tyson (TYS) to Chicago Midway International (MDW). It's 459 miles (739 km), about 1h 35m in the air. Operated by Allegiant Air.
Allegiant Air
Route data last updated: May 29, 2026
Airlines with non-stop flights
Alternative Routes
Other ways to fly from Knoxville to Chicago with one stop · direct emits 85 kg CO₂ per passenger
Looking for the return flight?
MDW → TYS: Flights from Chicago to KnoxvilleOther direct flights from Knoxville
Direct flights from Chicago (MDW)
Frequently Asked Questions
How long is the direct flight from Knoxville to Chicago?
A nonstop flight from Knoxville (TYS) to Chicago (MDW) takes approximately 1 hours and 35 minutes. The distance is 459 miles (739 km).
Which airlines fly nonstop from Knoxville to Chicago?
Just Allegiant Air.
Is there a nonstop flight from Knoxville to Chicago?
Yes. 1 airline: Allegiant Air.
How far is Knoxville from Chicago?
The flight distance from Knoxville to Chicago is 459 miles (739 km), measured as the great-circle (shortest air) distance. That's roughly the same distance as Mumbai to Goa.
What type of aircraft flies from Knoxville to Chicago?
At 1h 35m, this route typically uses narrow-body aircraft — Boeing 737 or Airbus A320. Varies by airline.
What is the carbon footprint of a flight from Knoxville to Chicago?
Roughly 85 kg CO2 per passenger one-way. That's about the same as driving 425 km.
Is the return flight from Chicago to Knoxville also nonstop?
Yes — nonstop flights run both ways. Flight time may differ slightly due to wind patterns.
When is the cheapest time to fly from Knoxville to Chicago?
Midweek flights (Tue/Wed) outside holiday peaks are usually cheapest. 3-6 weeks ahead is a good window for this route. Use "Check Prices" above to compare.
How early should I arrive at Mc Ghee Tyson for this flight?
1.5-2 hours for domestic. Add more time during holidays or busy travel weekends.