Direct (nonstop) flights from Knoxville to Key West
1 airline flys nonstop from Mc Ghee Tyson (TYS) to Key West International (EYW). It's 786 miles (1,265 km), about 2h 4m in the air. Operated by Allegiant Air.
Allegiant Air
Route data last updated: May 26, 2026
Airlines with non-stop flights
Alternative Routes
Other ways to fly from Knoxville to Key West with one stop · direct emits 145 kg CO₂ per passenger
Looking for the return flight?
EYW → TYS: Flights from Key West to KnoxvilleOther direct flights from Knoxville
Direct flights from Key West (EYW)
Frequently Asked Questions
How long is the direct flight from Knoxville to Key West?
A nonstop flight from Knoxville (TYS) to Key West (EYW) takes approximately 2 hours and 4 minutes. The distance is 786 miles (1,265 km).
Which airlines fly nonstop from Knoxville to Key West?
Just Allegiant Air.
Is there a nonstop flight from Knoxville to Key West?
Yes. 1 airline: Allegiant Air.
How far is Knoxville from Key West?
The flight distance from Knoxville to Key West is 786 miles (1,265 km), measured as the great-circle (shortest air) distance. That's roughly the same distance as London to Madrid.
What type of aircraft flies from Knoxville to Key West?
At 2h 4m, this route typically uses narrow-body or mid-range jets — Boeing 737 MAX or Airbus A320neo. Varies by airline.
What is the carbon footprint of a flight from Knoxville to Key West?
Roughly 145 kg CO2 per passenger one-way. That's about the same as driving 725 km.
Is the return flight from Key West to Knoxville also nonstop?
Yes — nonstop flights run both ways. Flight time may differ slightly due to wind patterns.
When is the cheapest time to fly from Knoxville to Key West?
Midweek flights (Tue/Wed) outside holiday peaks are usually cheapest. 3-6 weeks ahead is a good window for this route. Use "Check Prices" above to compare.
How early should I arrive at Mc Ghee Tyson for this flight?
1.5-2 hours for domestic. Add more time during holidays or busy travel weekends.