Direct (nonstop) flights from Knoxville to Tampa
1 airline flys nonstop from Mc Ghee Tyson (TYS) to Tampa International (TPA). It's 546 miles (878 km), about 1h 45m in the air. Operated by Southwest Airlines.
Southwest Airlines
Route data last updated: May 30, 2026
Airlines with non-stop flights
WN
Southwest Airlines
Alternative Routes
Other ways to fly from Knoxville to Tampa with one stop · direct emits 101 kg CO₂ per passenger
Looking for the return flight?
TPA → TYS: Flights from Tampa to KnoxvilleOther direct flights from Knoxville
Direct flights from Tampa (TPA)
Frequently Asked Questions
How long is the direct flight from Knoxville to Tampa?
A nonstop flight from Knoxville (TYS) to Tampa (TPA) takes approximately 1 hours and 45 minutes. The distance is 546 miles (878 km).
Which airlines fly nonstop from Knoxville to Tampa?
Just Southwest Airlines.
Is there a nonstop flight from Knoxville to Tampa?
Yes. 1 airline: Southwest Airlines.
How far is Knoxville from Tampa?
The flight distance from Knoxville to Tampa is 546 miles (878 km), measured as the great-circle (shortest air) distance.
What type of aircraft flies from Knoxville to Tampa?
At 1h 45m, this route typically uses narrow-body aircraft — Boeing 737 or Airbus A320. Varies by airline.
What is the carbon footprint of a flight from Knoxville to Tampa?
Roughly 101 kg CO2 per passenger one-way. That's about the same as driving 505 km.
Is the return flight from Tampa to Knoxville also nonstop?
Yes — nonstop flights run both ways. Flight time may differ slightly due to wind patterns.
When is the cheapest time to fly from Knoxville to Tampa?
Midweek flights (Tue/Wed) outside holiday peaks are usually cheapest. 3-6 weeks ahead is a good window for this route. Use "Check Prices" above to compare.
How early should I arrive at Mc Ghee Tyson for this flight?
1.5-2 hours for domestic. Add more time during holidays or busy travel weekends.