Direct (nonstop) flights from Tampa to Knoxville
1 airline flys nonstop from Tampa International (TPA) to Mc Ghee Tyson (TYS). It's 546 miles (878 km), about 1h 45m in the air. Operated by Southwest Airlines.
Southwest Airlines
Route data last updated: May 27, 2026
Airlines with non-stop flights
WN
Southwest Airlines
Alternative Routes
Other ways to fly from Tampa to Knoxville with one stop · direct emits 101 kg CO₂ per passenger
Looking for the return flight?
TYS → TPA: Flights from Knoxville to TampaOther direct flights from Tampa
Direct flights from Knoxville (TYS)
Frequently Asked Questions
How long is the direct flight from Tampa to Knoxville?
A nonstop flight from Tampa (TPA) to Knoxville (TYS) takes approximately 1 hours and 45 minutes. The distance is 546 miles (878 km).
Which airlines fly nonstop from Tampa to Knoxville?
Just Southwest Airlines.
Is there a nonstop flight from Tampa to Knoxville?
Yes. 1 airline: Southwest Airlines.
How far is Tampa from Knoxville?
The flight distance from Tampa to Knoxville is 546 miles (878 km), measured as the great-circle (shortest air) distance.
What type of aircraft flies from Tampa to Knoxville?
At 1h 45m, this route typically uses narrow-body aircraft — Boeing 737 or Airbus A320. Varies by airline.
What is the carbon footprint of a flight from Tampa to Knoxville?
Roughly 101 kg CO2 per passenger one-way. That's about the same as driving 505 km.
Is the return flight from Knoxville to Tampa also nonstop?
Yes — nonstop flights run both ways. Flight time may differ slightly due to wind patterns.
When is the cheapest time to fly from Tampa to Knoxville?
Midweek flights (Tue/Wed) outside holiday peaks are usually cheapest. 3-6 weeks ahead is a good window for this route. Use "Check Prices" above to compare.
How early should I arrive at Tampa International for this flight?
1.5-2 hours for domestic. Add more time during holidays or busy travel weekends.