Direct (nonstop) flights from Key West to Knoxville
1 airline flys nonstop from Key West International (EYW) to Mc Ghee Tyson (TYS). It's 786 miles (1,265 km), about 2h 15m in the air. Operated by Allegiant Air.
Allegiant Air
Route data last updated: May 26, 2026
Airlines with non-stop flights
Alternative Routes
Other ways to fly from Key West to Knoxville with one stop · direct emits 145 kg CO₂ per passenger
Looking for the return flight?
TYS → EYW: Flights from Knoxville to Key WestOther direct flights from Key West
Direct flights from Knoxville (TYS)
Frequently Asked Questions
How long is the direct flight from Key West to Knoxville?
A nonstop flight from Key West (EYW) to Knoxville (TYS) takes approximately 2 hours and 15 minutes. The distance is 786 miles (1,265 km).
Which airlines fly nonstop from Key West to Knoxville?
Just Allegiant Air.
Is there a nonstop flight from Key West to Knoxville?
Yes. 1 airline: Allegiant Air.
How far is Key West from Knoxville?
The flight distance from Key West to Knoxville is 786 miles (1,265 km), measured as the great-circle (shortest air) distance. That's roughly the same distance as London to Madrid.
What type of aircraft flies from Key West to Knoxville?
At 2h 15m, this route typically uses narrow-body or mid-range jets — Boeing 737 MAX or Airbus A320neo. Varies by airline.
What is the carbon footprint of a flight from Key West to Knoxville?
Roughly 145 kg CO2 per passenger one-way. That's about the same as driving 725 km.
Is the return flight from Knoxville to Key West also nonstop?
Yes — nonstop flights run both ways. Flight time may differ slightly due to wind patterns.
When is the cheapest time to fly from Key West to Knoxville?
Midweek flights (Tue/Wed) outside holiday peaks are usually cheapest. 3-6 weeks ahead is a good window for this route. Use "Check Prices" above to compare.
How early should I arrive at Key West International for this flight?
1.5-2 hours for domestic. Add more time during holidays or busy travel weekends.