Direct (nonstop) flights from New Orleans to Knoxville
1 airline flys nonstop from Louis Armstrong New Orleans International (MSY) to Mc Ghee Tyson (TYS). It's 541 miles (871 km), about 2h in the air. Operated by American Airlines.
American Airlines
Route data last updated: May 28, 2026
Airlines with non-stop flights
AA
American Airlines
Alternative Routes
Other ways to fly from New Orleans to Knoxville with one stop · direct emits 100 kg CO₂ per passenger
Looking for the return flight?
TYS → MSY: Flights from Knoxville to New OrleansOther direct flights from New Orleans
Direct flights from Knoxville (TYS)
Frequently Asked Questions
How long is the direct flight from New Orleans to Knoxville?
A nonstop flight from New Orleans (MSY) to Knoxville (TYS) takes approximately 2 hours. The distance is 541 miles (871 km).
Which airlines fly nonstop from New Orleans to Knoxville?
Just American Airlines.
Is there a nonstop flight from New Orleans to Knoxville?
Yes. 1 airline: American Airlines.
How far is New Orleans from Knoxville?
The flight distance from New Orleans to Knoxville is 541 miles (871 km), measured as the great-circle (shortest air) distance.
What type of aircraft flies from New Orleans to Knoxville?
At 2h, this route typically uses narrow-body aircraft — Boeing 737 or Airbus A320. Varies by airline.
What is the carbon footprint of a flight from New Orleans to Knoxville?
Roughly 100 kg CO2 per passenger one-way. That's about the same as driving 500 km.
Is the return flight from Knoxville to New Orleans also nonstop?
Yes — nonstop flights run both ways. Flight time may differ slightly due to wind patterns.
When is the cheapest time to fly from New Orleans to Knoxville?
Midweek flights (Tue/Wed) outside holiday peaks are usually cheapest. 3-6 weeks ahead is a good window for this route. Use "Check Prices" above to compare.
How early should I arrive at Louis Armstrong New Orleans International for this flight?
1.5-2 hours for domestic. Add more time during holidays or busy travel weekends.