Direct (nonstop) flights from Knoxville to New Orleans
1 airline flys nonstop from Mc Ghee Tyson (TYS) to Louis Armstrong New Orleans International (MSY). It's 541 miles (871 km), about 1h 55m in the air. Operated by American Airlines.
American Airlines
Route data last updated: May 30, 2026
Airlines with non-stop flights
AA
American Airlines
Alternative Routes
Other ways to fly from Knoxville to New Orleans with one stop · direct emits 100 kg CO₂ per passenger
Looking for the return flight?
MSY → TYS: Flights from New Orleans to KnoxvilleOther direct flights from Knoxville
Direct flights from New Orleans (MSY)
Frequently Asked Questions
How long is the direct flight from Knoxville to New Orleans?
A nonstop flight from Knoxville (TYS) to New Orleans (MSY) takes approximately 1 hours and 55 minutes. The distance is 541 miles (871 km).
Which airlines fly nonstop from Knoxville to New Orleans?
Just American Airlines.
Is there a nonstop flight from Knoxville to New Orleans?
Yes. 1 airline: American Airlines.
How far is Knoxville from New Orleans?
The flight distance from Knoxville to New Orleans is 541 miles (871 km), measured as the great-circle (shortest air) distance.
What type of aircraft flies from Knoxville to New Orleans?
At 1h 55m, this route typically uses narrow-body aircraft — Boeing 737 or Airbus A320. Varies by airline.
What is the carbon footprint of a flight from Knoxville to New Orleans?
Roughly 100 kg CO2 per passenger one-way. That's about the same as driving 500 km.
Is the return flight from New Orleans to Knoxville also nonstop?
Yes — nonstop flights run both ways. Flight time may differ slightly due to wind patterns.
When is the cheapest time to fly from Knoxville to New Orleans?
Midweek flights (Tue/Wed) outside holiday peaks are usually cheapest. 3-6 weeks ahead is a good window for this route. Use "Check Prices" above to compare.
How early should I arrive at Mc Ghee Tyson for this flight?
1.5-2 hours for domestic. Add more time during holidays or busy travel weekends.